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Fig. 4 | Molecular Brain

Fig. 4

From: PDZD8-deficient mice manifest behavioral abnormalities related to emotion, cognition, and adaptation due to dyslipidemia in the brain

Fig. 4

Anxiety and fear-related behavior of PDZD8-KO mice. a–d Distance traveled in the light and dark chambers (a), time spent in the light and dark chambers (b), number of transitions between the light and dark chambers (c), and latency of entry into the light chamber (d) for the light–dark transition test. e–h, Distance traveled (e), vertical activity (f), center time (g), and stereotypic counts (h) for the open-field test. i–l, Distance traveled (i), total number of arm entries (j), percentage of entries into the open arms (k), and percent time spent in the open arms (l) for the elevated plus-maze test. All data are means ± s.e.m. (WT mice, n = 18; PDZD8-KO mice, n = 19 for a–d and n = 18 for e–l). P values for differences between genotypes were determined with Student’s t test (a–c, k), the Mann–Whitney U test (d, i, j, l), or two-way repeated-measures ANOVA (e–h). *P < 0.05, ***P < 0.001; n.s., not significant. The results of all statistical analysis are provided in Additional file 2: Table S2

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