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Fig. 4 | Molecular Brain

Fig. 4

From: Contraction of human brain vascular pericytes in response to islet amyloid polypeptide is reversed by pramlintide

Fig. 4

Treatments modifying the effect of oIAPP on HBVP. CLS after stimulation with vehicle (A), oIAPP alone (B), and oIAPP together with either Y27632 (C), pramlintide (D) or blebbistatin (E), scale bar (A-E): 100 µm. Graphs in (F) and (G) show quantification of the proportion of round-shaped HBVP per CLS after stimulation. All images were acquired with the 10 × objective. Experiments in (F) and (G) were performed in 6 replicates and data was analyzed using one-way ANOVA followed by Tuckey test with (n = 6) comparisons (F) or (n = 3) comparisons (G). Each point represent the mean ± SD. Significant difference at **p < 0.01, ***p < 0.001

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