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Table 1 Clinical data of individuals included in the study

From: Contraction of human brain vascular pericytes in response to islet amyloid polypeptide is reversed by pramlintide

Sex

Age (years)

ABC1 staging

LB2 (0–6)

T2DM

IAPP levels (pg/ml)

Postmortem delay (h:min)

Cause of death

M

70

A0B1C0

3

No

4.83

6:20

Pneumonia + cardiogenic shock

M

63

A0B1C0

0

Yes

5.18

5:00

Unclear, possible infection

M

75

A2B1C1*

0

No

5.70

7:10

Cardiac arrest with COPD

F

60

A0B0C0

0

No

6.05

8:10

Breast cancer with metastasis

F

92

A0B2C0

1

No

13.63

6:35

Heart failure

F

68

A0B0C0

0

Yes

13.67

4:30

Euthanasia

M

102

A1B2C1*

0

No

14.54

5:00

Ileus

F

69

A0B0C0

0

Yes

15.93

5:25

Cachexia and infection

  1. 1ABC Montine staging of Alzheimer’s disease. A0-3: stain for Aβ/amyloid plaques. B0-3: stain for neurofibrillary tangles. C0-3: stain for neuritic plaques. 2LB: 0–6 Lewy Body staging according to Braak. T2DM: Type 2 Diabetes Mellitus. COPD: chronic obstructive pulmonary disease *0–2 diffuse amyloid plaques found in CA1