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Fig. 1 | Molecular Brain

Fig. 1

From: Properties of Nav1.8ChR2-positive and Nav1.8ChR2-negative afferent mechanoreceptors in the hindpaw glabrous skin of mice

Fig. 1

Behavioral responses to mechanical and light stimulation at the hindpaws of Nav1.8ChR2 mice. A Frequency of hindpaw avoidance in response to cotton swab strikes in Nav1.8ChR2 mice (n = 23). B Frequency of hindpaw avoidance in response to mechanical stimulation by 0.69-mN (left bar, n = 17) and 3.92-mN von Frey filaments (right bar, n = 17) in Nav1.8ChR2 mice. C The 50% threshold of hindpaw avoidance responses assessed by von Frey filaments using the up-down method in Nav1.8ChR2 mice (n = 11). D Frequency of hindpaw avoidance in response to the stimulation by blue laser light at intensities from 1 to 100 mW/mm2 (n = 5 to 22). E Scores of nocifensive responses induced by blue laser light at intensities from 1 to 100 mW/mm2 (n = 5 to 22). Data represent individual observations and/or mean ± SEM, *p < 0.05

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