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Fig. 4 | Molecular Brain

Fig. 4

From: Properties of Nav1.8ChR2-positive and Nav1.8ChR2-negative afferent mechanoreceptors in the hindpaw glabrous skin of mice

Fig. 4

Comparison of properties between Nav1.8ChR2-positive and Nav1.8ChR2-negative Aδ-fiber mechanoreceptors. A, B Two sets of sample traces show AP impulses evoked by indentations (5, 30, and 80 mN) in a Nav1.8ChR2-positive Aδ-fiber SA-mechanoreceptor (A) and a Nav1.8ChR2-negative Aδ-fiber RA-mechanoreceptors (B). C Percent of Nav1.8ChR2-positive and Nav1.8ChR2-negative Aδ-fiber mechanoreceptors that display SA impulses or RA impulses. Recordings numbers are indicated in the bars. D Conduction velocity of Nav1.8ChR2-positive and Nav1.8ChR2-negative Aδ-fiber mechanoreceptors. E Frequency of AP impulses evoked by different forces (5, 30, and 80 mN) in Nav1.8ChR2-positive Aδ-fiber SA-mechanoreceptors and Nav1.8ChR2-negative Aδ-fiber RA-mechanoreceptors. F, G Indenter (F) and von Frey (G) force thresholds for evoking AP impulses in Nav1.8ChR2-positive Aδ-fiber RA-mechanoreceptors (n = 1), Nav1.8ChR2-positive Aδ-fiber SA-mechanoreceptors (n = 13), Nav1.8ChR2-negative Aδ-fiber RA-mechanoreceptors (n = 9), and Nav1.8ChR2-negative Aδ-fiber SA-mechanoreceptors (n = 2). Data represent individual observations and/or mean ± SEM, *p < 0.05, ***p < 0.001

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