Fig. 5

Properties of Nav1.8^ChR2-positive C-fiber mechanoreceptors. A Sample traces show SA impulses evoked by indentations (5, 30, 80 mN) in a Nav1.8^ChR2-positive C-fiber SA-mechanoreceptor. B Frequency of impulses evoked by different indentation forces in Nav1.8^ChR2-positive C-fiber SA-mechanoreceptors (n = 14) and a Nav1.8^ChR2-positive C-fiber RA-mechanoreceptor (n = 1). C Conduction velocity of Nav1.8^ChR2-positive C-fiber SA-mechanoreceptors (n = 16) and a Nav1.8^ChR2-positive C-fiber RA-mechanoreceptor (n = 1). D, E Indenter (D) and von Frey (E) force thresholds for evoking AP impulses in Nav1.8^ChR2-positive C-fiber SA-mechanoreceptors (n = 16) and a Nav1.8^ChR2-positive C-fiber RA-mechanoreceptor (n = 1). Data represent individual observations and/or mean ± SEM