Fig. 1

General health and sensory and motor functions in 5-HTT-deficient mice. a Body weight (g), b body temperature (°C), c grip strength (Newton, N), d wire hang latency (s), e latency to paw lick or foot shake (s) in the hot plate test, f latency to fall off a rotating rod (s) in the rotarod test, g acoustic startle response to sound stimuli (110 and 120 dB white noise), and h prepulse inhibition (%) of the startle response with 74 and 78 dB prepulse stimuli. Values are means ± SEM. Asterisks and daggers indicate statistically significant differences between groups (5-HTT−/− vs. 5-HTT+/+, *p < 0.05 and **p < 0.01; 5-HTT−/− vs. 5-HTT+/−, ^†p < 0.05 and ^††p < 0.01)