Skip to main content
Fig. 5 | Molecular Brain

Fig. 5

From: Tibial fracture surgery in elderly mice caused postoperative neurocognitive disorder via SOX2OT lncRNA in the hippocampus

Fig. 5

SOX2OT knockdown protected against LPS-induced mitochondrial dysfunction in HT22 cells. a Mitochondria-derived superoxide was stained with the MitoSox probe, and intracellular oxidants were stained with cellular ROS dye. Original magnification × 600; n = 4. b, c Statistical analysis of cellular ROS fluorescence density and MitoSox fluorescence in HT22 cells (fold over Lv + nc); n = 4. d–e Seahorse analysis showing OCR and quantitative statistical analysis of OCR. *P < 0.05 vs. Lv-neg; **P < 0.01, ****P < 0.01 vs. Lv-neg; ##P < 0.01 vs. Lv-neg; &&&P < 0.01 vs. Lv-neg + LPS; n = 5

Back to article page