Skip to main content
Fig. 3 | Molecular Brain

Fig. 3

From: Maturation of nucleus accumbens synaptic transmission signals a critical period for the rescue of social deficits in a mouse model of autism spectrum disorder

Fig. 3

Comparison of the developmental profile of spontaneous excitatory and inhibitory frequency between C57BL/6J and BTBR mice. Within-cell comparison of the difference in the frequency of spontaneous excitation and inhibition (E-I frequency) showed a shift toward increased inhibition in P30 BTBR mice relative to C57BL/6J mice. *p < 0.05. sEPSC: C57BL/6J: P4 (9 cells/4 mice), P6 (9 cells/3 mice), P8 (15 cells/4 mice), P12 (9 cells/ 3 mice), P15 (11 cells/ 4 mice), P21 (9 cells/ 3 mice), P30 (9 cells/ 3 mice); BTBR: P4 (10 cells/3 mice), P6 (10 cells/3 mice), P8 (18 cells/5 mice), P12 (10 cells/ 3 mice), P15 (8 cells/ 3 mice), P21 (8 cells/ 3 mice), P30 (9 cells/ 3 mice)

Back to article page

Molecular Brain

ISSN: 1756-6606