Skip to main content

Articles

Page 13 of 27

  1. The selective serotonin reuptake inhibitor fluoxetine (FLX) is widely used to treat depression and anxiety disorders. Chronic FLX treatment reportedly induces cellular responses in the brain, including increas...

    Authors: Koji Ohira, Hideo Hagihara, Miki Miwa, Katsuki Nakamura and Tsuyoshi Miyakawa
    Citation: Molecular Brain 2019 12:69
    Content type: Research Published on:

  2. Post-traumatic stress disorder (PTSD) is a psychiatric disorder associated with memories of traumatic experiences. Recent studies have shown that the forgetting of contextual fear memory is promoted via increa...

    Authors: Rie Ishikawa, Chiaki Uchida, Shiho Kitaoka, Tomoyuki Furuyashiki and Satoshi Kida
    Citation: Molecular Brain 2019 12:68
    Content type: Short report Published on:

  3. LIMK1 and LIMK2 are key downstream targets to mediate the effects of the Rho family small GTPases and p21-activated kinases (PAK) in the regulation of the actin cytoskeleton. LIMKs are also critical for synapt...

    Authors: Rui Mao, Rui Deng, Yan Wei, Lifang Han, Yanghong Meng, Wei Xie and Zhengping Jia
    Citation: Molecular Brain 2019 12:67
    Content type: Research Published on:

  4. Poly-arginine peptide-18 (R18) has recently emerged as a highly effective neuroprotective agent in experimental stroke models, and is particularly efficacious in protecting cortical neurons against glutamic ac...

    Authors: Gabriella MacDougall, Ryan S. Anderton, Frank L. Mastaglia, Neville W. Knuckey and Bruno P. Meloni
    Citation: Molecular Brain 2019 12:66
    Content type: Research Published on:

  5. Protein synthesis is crucial for maintaining synaptic plasticity and synaptic signalling. Here we have attempted to understand the role of RNA binding proteins, Fragile X Mental Retardation Protein (FMRP) and ...

    Authors: Preeti Madhav Kute, Sarayu Ramakrishna, Nagammal Neelagandan, Sumantra Chattarji and Ravi. S. Muddashetty
    Citation: Molecular Brain 2019 12:65
    Content type: Research Published on:

  6. Glutamate receptors of the N-methyl-D-aspartate (NMDA) family are coincident detectors of pre- and postsynaptic activity, allowing Ca2+ influx into neurons. These properties are central to neurological disease me...

    Authors: Hannah Warming, Chrysia-Maria Pegasiou, Aleksandra P. Pitera, Hanna Kariis, Steven D. Houghton, Ksenia Kurbatskaya, Aminul Ahmed, Paul Grundy, Girish Vajramani, Diederik Bulters, Xavier Altafaj, Katrin Deinhardt and Mariana Vargas-Caballero
    Citation: Molecular Brain 2019 12:64
    Content type: Short report Published on:

  7. The transcription factor Foxg1 is known to be continuously expressed at a high level in mature neurons in the telencephalon, but little is known about its role in neural plasticity. Mutations in human FOXG1 cause...

    Authors: Baocong Yu, Junhua Liu, Mingzhao Su, Chunlian Wang, Huanxin Chen and Chunjie Zhao
    Citation: Molecular Brain 2019 12:63
    Content type: Research Published on:

  8. This study describes the interaction between Cav2 calcium channels and Rabconnectin-3, a di-subunit protein that is associated with synaptic vesicles. Immunostaining reveals that both Rabconnectin-3α (RB-3α) a...

    Authors: Maria A. Gandini, Ivana A. Souza, Jing Fan, Katherine Li, Decheng Wang and Gerald W. Zamponi
    Citation: Molecular Brain 2019 12:62
    Content type: Short report Published on:

  9. The human-immunodeficiency virus (HIV) envelope protein gp120 promotes synaptic damage similar to that observed in people living with HIV who have neurocognitive disorders. The neurotoxic effect of gp120 appea...

    Authors: Valeria Avdoshina, Francesca Taraballi, Ennio Tasciotti, Aykut Ãœren and Italo Mocchetti
    Citation: Molecular Brain 2019 12:61
    Content type: Micro report Published on:

  11. Recessive mutations in the ubiquitously expressed POLR3A and POLR3B genes are the most common cause of POLR3-related hypomyelinating leukodystrophy (POLR3-HLD), a rare childhood-onset disorder characterized by de...

    Authors: Karine Choquet, Maxime Pinard, Sharon Yang, Robyn D. Moir, Christian Poitras, Marie-Josée Dicaire, Nicolas Sgarioto, Roxanne Larivière, Claudia L. Kleinman, Ian M. Willis, Marie-Soleil Gauthier, Benoit Coulombe and Bernard Brais
    Citation: Molecular Brain 2019 12:59
    Content type: Short report Published on:

  13. Go is a member of the pertussis toxin-sensitive Gi/o family. Despite its abundance in the central nervous system, the precise role of Go remains largely unknown compared to other G proteins. In the present study,...

    Authors: Hye Lim Cha, Jung-Mi Choi, Huy-Hyen Oh, Narayan Bashyal, Sung-Soo Kim, Lutz Birnbaumer and Haeyoung Suh-Kim
    Citation: Molecular Brain 2019 12:57
    Content type: Research Published on:

  14. Fragile X syndrome (FXS) is a neurodevelopmental disorder caused by silencing of the FMR1 gene and subsequent loss of its protein product, fragile X retardation protein (FMRP). One of the most robust neuropatholo...

    Authors: Frankie H. F. Lee, Terence K. Y. Lai, Ping Su and Fang Liu
    Citation: Molecular Brain 2019 12:56
    Content type: Research Published on:

  15. Synaptic abnormalities, perturbed endosomal recycling mediated by loss of the small GTPase RAB11, and neuroinflammatory signaling have been associated with multiple neurodegenerative diseases including the mot...

    Authors: Joy Mitra, Pavana M. Hegde and Muralidhar L. Hegde
    Citation: Molecular Brain 2019 12:55
    Content type: Micro report Published on:

  16. Gene expression is highly regulated to functionally diversify cells. Genes that cooperate in the same physiological processes occasionally reside within nearby regions in a chromosome. Olfactory marker protein...

    Authors: Noriyuki Nakashima, Kie Nakashima, Akiko Takaku-Nakashima and Makoto Takano
    Citation: Molecular Brain 2019 12:54
    Content type: Short report Published on:

  17. The growth cone is essential for nerve growth and axon regeneration, which directly form and rearrange the neural network. Recently, to clarify the molecular signaling pathways in the growth cone that utilize ...

    Authors: Michihiro Igarashi and Shujiro Okuda
    Citation: Molecular Brain 2019 12:53
    Content type: Micro report Published on:

  18. Mushroom body (MB) is a prominent structure essential for olfactory learning and memory in the Drosophila brain. The development of the MB involves the appropriate guidance of axon lobes and sister axon branch...

    Authors: Huaixing Kang, Juan Zhao, Xuan Jiang, Guangxu Li, Wen Huang, Huili Cheng and Ranhui Duan
    Citation: Molecular Brain 2019 12:52
    Content type: Research Published on:

  19. Protein phosphorylation plays an important role in learning and memory. Protein phosphatase 2A (PP2A) is a serine/threonine phosphatase involved in the regulation of neural synaptic plasticity. Here, to determ...

    Authors: Jing Wang, Ran Xie, Xiaolin Kou, Yu Liu, Cui Qi, Rui Liu, Weiyan You, Jun Gao and Xiang Gao
    Citation: Molecular Brain 2019 12:51
    Content type: Research Published on:

  20. Neonatal seizures are different from adult seizures, and many antiepileptic drugs that are effective in adults often fail to treat neonates. Here, we report that gluconate inhibits neonatal seizure by inhibiti...

    Authors: Zheng Wu, Qingwei Huo, Liang Ren, Fengping Dong, Mengyang Feng, Yue Wang, Yuting Bai, Bernhard Lüscher, Sheng-Tian Li, Guan-Lei Wang, Cheng Long, Yun Wang, Gangyi Wu and Gong Chen
    Citation: Molecular Brain 2019 12:50
    Content type: Research Published on:

  21. MicroRNAs (miRNAs) are endogenous small (18–25 nt), single-stranded, non-coding RNAs that play key roles in post-transcriptional gene expression regulation. The expression profiles of miRNAs in biofluids and t...

    Authors: Hisashi Uwatoko, Yuka Hama, Ikuko Takahashi Iwata, Shinichi Shirai, Masaaki Matsushima, Ichiro Yabe, Jun Utsumi and Hidenao Sasaki
    Citation: Molecular Brain 2019 12:49
    Content type: Research Published on:

  23. Following publication of the original article [1], the authors reported that one of the authors’ names was spelled incorrectly.

    Authors: Mikiei Tanaka, Hongyun Li, Xijun Zhang, Jatinder Singh, Clifton L. Dalgard, Matthew Wilkerson and Yumin Zhang
    Citation: Molecular Brain 2019 12:47
    Content type: Correction Published on:

    The original article was published in Molecular Brain 2019 12:25

  24. The microgravity environment in space can impact astronauts’ cognitive and behavioral activities. However, due to the limitations of research conditions, studies of biological changes in the primate brain, suc...

    Authors: Xu Zhang, Xixia Chu, Lei Chen, Juan Fu, Shuai Wang, Jinjing Song, Guanghan Kan, Weizhong Jiang, Guang He, Xiaoping Chen and Weidong Li
    Citation: Molecular Brain 2019 12:46
    Content type: Micro report Published on:

  25. Glioblastoma exhibits phenotypic and genetic heterogeneity, aggressive invasiveness, therapeutic resistance, and tumor recurrence, which can be explained by the existence of glioma stem cells (GSCs). In this s...

    Authors: Ryota Tamura, Hiroyuki Miyoshi, Oltea Sampetrean, Munehisa Shinozaki, Yukina Morimoto, Chizuru Iwasawa, Raita Fukaya, Yutaka Mine, Hirotaka Masuda, Tetsuo Maruyama, Minoru Narita, Hideyuki Saya, Kazunari Yoshida, Hideyuki Okano and Masahiro Toda
    Citation: Molecular Brain 2019 12:45
    Content type: Research Published on:

  27. To prevent or ameliorate Alzheimer’s disease (AD) we must understand its molecular basis. AD develops over decades but detailed molecular analysis of AD brains is limited to postmortem tissue where the stresse...

    Authors: Morgan Newman, Nhi Hin, Stephen Pederson and Michael Lardelli
    Citation: Molecular Brain 2019 12:43
    Content type: Micro report Published on:

  30. Results of recent genome-wide association studies (GWAS) and whole genome sequencing (WGS) highlighted type II cadherins as risk genes for autism spectrum disorders (ASD). To determine whether these cadherins ...

    Authors: Chunlei Wang, Yi-Hsuan Pan, Yue Wang, Gene Blatt and Xiao-Bing Yuan
    Citation: Molecular Brain 2019 12:40
    Content type: Research Published on:

  31. TMP21, a type I transmembrane protein of thep24 protein family, mediates protein trafficking and maturation. Dysregulation of TMP21 is implicated in the pathogenesis of Alzheimer’s disease (AD). However, under...

    Authors: Xiaojie Zhang, Yili Wu, Fang Cai and Weihong Song
    Citation: Molecular Brain 2019 12:39
    Content type: Research Published on:

  32. Itch contagion has been reported in human when people watch someone scratching in a video. The basic mechanism of contagious itch induced by scratching video is still being investigated. A recent study has rep...

    Authors: Jing-Shan Lu, Qi-Yu Chen, Si-Bo Zhou, Feng-Yi Wu, Ren-Hao Liu, Zhao-Xiang Zhou, Hua Zhang and Min Zhuo
    Citation: Molecular Brain 2019 12:38
    Content type: Research Published on:

  33. Genetic and pharmacological manipulations targeting metabotropic glutamate receptor 5 (mGluR5) affect performance in behavioural paradigms that depend on cognitive flexibility. Many of these studies involved e...

    Authors: Jisoo Lim, Eosu Kim, Hyun Jong Noh, Shinwon Kang, Benjamin U. Phillips, Dong Goo Kim, Timothy J. Bussey, Lisa Saksida, Christopher J. Heath and Chul Hoon Kim
    Citation: Molecular Brain 2019 12:37
    Content type: Research Published on:

  34. Chronic pain is commonly accompanied with anxiety disorder, which complicates treatment. In this study, we investigated the analgesic and anxiolytic effects of Formononetin (FMNT), an active component of tradi...

    Authors: Xin-shang Wang, Shao-yu Guan, An Liu, Jiao Yue, Li-ning Hu, Kun Zhang, Liu-kun Yang, Liang Lu, Zhen Tian, Ming-gao Zhao and Shui-bing Liu
    Citation: Molecular Brain 2019 12:36
    Content type: Research Published on:

  35. Huntington’s disease (HD) is a neurodegenerative disorder caused by a genetic abnormality in the huntingtin gene that leads to a polyglutamine repeat expansion of the huntingtin protein. The cleaved polyglutam...

    Authors: Khaled S. Abd-Elrahman and Stephen S. G. Ferguson
    Citation: Molecular Brain 2019 12:35
    Content type: Short report Published on:

  36. The physiological functions controlled by T-type channels are intrinsically dependent on their gating properties, and alteration of T-type channel activity is linked to several human disorders. Therefore, it i...

    Authors: Bohumila Jurkovicova-Tarabova, Leos Cmarko, Renata Rehak, Gerald W. Zamponi, Lubica Lacinova and Norbert Weiss
    Citation: Molecular Brain 2019 12:34
    Content type: Research Published on:

  37. Autophagy allows for lysosomal cellular degradation of cytosolic components. In particular, neuronal autophagy is essential for cellular homeostasis and neuronal survival and is tightly regulated by several au...

    Authors: Pureum Jeon, Ju-Hui Park, Yong-Woo Jun, You-Kyung Lee, Deok-Jin Jang and Jin-A Lee
    Citation: Molecular Brain 2019 12:33
    Content type: Micro report Published on:

  38. Calcium/Calmodulin-dependent protein kinase II (CaMKII) plays a key role in the molecular mechanism of memory formation. CaMKII is known to be activated specifically in the activated spines during memory forma...

    Authors: Sanghyun Ye, Ji-il Kim, Jooyoung Kim and Bong-Kiun Kaang
    Citation: Molecular Brain 2019 12:32
    Content type: Micro report Published on:

  39. Merkel discs, located in skin touch domes and whisker hair follicles, are tactile end organs essential for environmental exploration, social interaction, and tactile discrimination. Recent studies from our gro...

    Authors: Mayumi Sonekatsu, Steven Lawrence Gu, Hirosato Kanda and Jianguo G. Gu
    Citation: Molecular Brain 2019 12:31
    Content type: Micro report Published on:

  40. Theta-burst stimulation (TBS) induces short-term potentiation (STP) plus two types of transcriptionally-independent forms of long-term potentiation (LTP), termed LTP1 and LTP2. We have compared the susceptibil...

    Authors: Pojeong Park, Thomas M. Sanderson, Zuner A. Bortolotto, John Georgiou, Min Zhuo, Bong-Kiun Kaang and Graham L. Collingridge
    Citation: Molecular Brain 2019 12:30
    Content type: Micro report Published on:

  41. Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed antidepressant drugs in pregnant women. Infants born following prenatal exposure to SSRIs have a higher risk for behavioral abnormalities...

    Authors: Weonjin Yu, Yi-Chun Yen, Young-Hwan Lee, Shawn Tan, Yixin Xiao, Hidayat Lokman, Audrey Khoo Tze Ting, Hasini Ganegala, Taejoon Kwon, Won-Kyung Ho and H. Shawn Je
    Citation: Molecular Brain 2019 12:29
    Content type: Research Published on:

  43. The amyloid precursor protein (APP) is endoproteolytically processed to generate either the neurotoxic beta-amyloid peptide (Aβ) or the secreted ectodomain APP alpha (sAPPα). While neurotrophic properties of s...

    Authors: Christian Tackenberg and Roger M. Nitsch
    Citation: Molecular Brain 2019 12:27
    Content type: Micro report Published on:

  44. A major barrier to the effective conduct of clinical trials of new drug candidates against Alzheimer’s disease (AD) and to identifying patients for receiving future disease-modifying treatments is the limited ...

    Authors: Henrik Zetterberg and Samantha C. Burnham
    Citation: Molecular Brain 2019 12:26
    Content type: Review Published on:

  45. Posttraumatic stress disorder is developed by exposure to a threatening and/or a horrifying event and characterized by the presence of anxiety, hyperarousal, avoidance, and sleep abnormality for a prolonged pe...

    Authors: Mikiei Tanaka, Hongyun Li, Xijun Zhang, Jatinder Singh, Clifton L. Dalgard, Matthew Wilkerson and Yumin Zhang
    Citation: Molecular Brain 2019 12:25
    Content type: Research Published on:

    The Correction to this article has been published in Molecular Brain 2019 12:47

  47. It is now generally accepted that the extra-skeleton functionalities of bone are multifaceted. Its endocrine functions came first to light when it was realized that osteoblasts, the bone forming cells, maintai...

    Authors: Chang Shan, Arijit Ghosh, Xing-zhi Guo, Shu-min Wang, Yan-fang Hou, Sheng-tian Li and Jian-min Liu
    Citation: Molecular Brain 2019 12:23
    Content type: Review Published on:

  49. Information from direct experience and observation of others is integrated in the brain to enable appropriate responses to environmental stimuli. Fear memory can be acquired by observing a conspecific’s distre...

    Authors: Hiroshi Nomura, Chie Teshirogi, Daisuke Nakayama, Masabumi Minami and Yuji Ikegaya
    Citation: Molecular Brain 2019 12:21
    Content type: Research Published on:

  50. A number of neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis, share intra- and/or extracellular deposition of protein aggregates as a common cor...

    Authors: Jae-Young Koh, Ha Na Kim, Jung Jin Hwang, Yang-Hee Kim and Sang Eun Park
    Citation: Molecular Brain 2019 12:18
    Content type: Review Published on:
Submit manuscript

Affiliated with

Annual Journal Metrics

  • 2022 Citation Impact
    3.6 - 2-year Impact Factor
    4.6 - 5-year Impact Factor
    0.901 - SNIP (Source Normalized Impact per Paper)
    1.273 - SJR (SCImago Journal Rank)

    2023 Speed
    13 days submission to first editorial decision for all manuscripts (Median)
    70 days submission to accept (Median)

    2023 Usage 
    958,127 downloads
    499 Altmetric mentions

New Content Item

Molecular Brain is a member of the Neuroscience Peer Review Consortium.

New Content Item (1)
Molecular Brain has partnered with Publons to give you official recognition for your contribution to peer review. Create a free profile to have your reviews automatically added. 


Follow

Molecular Brain

ISSN: 1756-6606