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Table 2 Effects of Ro25-6981 on LTP induced by different protocols in the anterior cingulate cortex (ACC) and hippocampal CA1 region

From: Induction- and conditioning-protocol dependent involvement of NR2B-containing NMDA receptors in synaptic potentiation and contextual fear memory in the hippocampal CA1 region of rats

Induction Protocol

ACC (Zhao et al., 2005)

CA1 (the present study)

Spike timing protocol

LTP blocked

LTP reduced or blocked

Pairing protocol

LTP reduced

Normal LTP

HFS protocol


Normal LTP