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Featured article: Criteria for identifying the molecular basis of the engram (CaMKII, PKMzeta)

In 2016 John Lisman accepted an invitation from the editors of Molecular Brain to contribute an article to our series of mini-reviews on Molecules of Memory.  We received his article on 'Criteria for Identifying the Molecular Basis of the Engram (CaMKII, PKMzeta)’ in September 2017 and it went out to referees in the usual way.  In October 2017, before the review process was complete, we heard the sad news of John’s death.  As a tribute to his outstanding theoretical and experimental contributions to many aspects of brain function, but particularly to the understanding of the neural basis of learning, we are publishing his paper as submitted.  We hope to publish a collection of commentaries on his paper at a later date.

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Rong Wu et al. Schematic representation of the role of TREM2 in cerebral ischemia/reperfusion injury (Figure 8)

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Article Collection - Molecules of Neural Disorders

In this series of reviews, we take a look at the molecular basis of neural disorders. The topics addressed include: iPSC technology for autism models, CaMKII dysregulation in Alzheimer's disease, migroglia in neuropathic pain, metabotropic glutamate receptors in schizophrenia, and cortical kinate receptors in anxiety. 

Aims and scope

Molecular Brain is an open access, peer-reviewed journal that considers manuscripts on all aspects of studies on the nervous system at the molecular, cellular, and systems level providing a forum for scientists to communicate their findings.

Molecular brain research is a rapidly expanding research field in which integrative approaches at the genetic, molecular, cellular and synaptic levels yield key information about the physiological and pathological brain. These studies involve the use of a wide range of modern techniques in molecular biology, genomics, proteomics, imaging and electrophysiology.

No major experimental revisions requested. We will not request major additional experiments during the peer-review process, as we believe that high-quality data should be published promptly without unnecessary delay.

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About the society

Molecular Brain is the official journal of the Association for the Study of Neurons and Diseases (AND). The AND is a not-for-profit organization for the study of mental health from a neurological perspective. The goal of AND is to enhance the quality and quantity of research and education as it pertains to the understanding and treatment of mental health issues.

BK Kaang

Editors' quotes

“The brain is the most complex structure in the universe, yet it defines who we are. Molecular Brain is a fast, open access, online journal that publishes high quality papers and thus promotes communication among neuroscientists interested in revealing the mysteries of brain function at the molecular and cellular level."

Bong-Kiun Kaang, Editor-in-Chief, Molecular Brain

Tim Bliss

 “It is our goal at Molecular Brain to offer a rapid and open access forum for papers that illuminate the molecular mechanisms underpinning the cellular, network and cognitive aspects of brain function. There is no field in 21st century science that is advancing with such astonishing rapidity, and we hope that Molecular Brain will reflect this excitement.”

Tim Bliss, Editor-in-Chief, Molecular Brain

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"One of the most significant driving forces in science is discovery in our daily research activity. At Molecular Brain, we believe the delay between the moment of discovery and publication should be as short as possible, but with high-quality and fair peer-review. By exploring and adopting new innovations and technology advances, I will strive to ensure Molecular Brain is the best place to publish your discovery in brain science. "

Tsuyoshi Miyakawa, Editor-in-Chief


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Molecular Brain is a member of the Neuroscience Peer Review Consortium.

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