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Figure 5 | Molecular Brain

Figure 5

From: Rab-mediated vesicular transport is required for neuronal positioning in the developing Drosophila visual system

Figure 5

Rab5 and Rab11 mutations enhanced the RN-tre overexpression eye phenotype. (A) Ovexpression of RN-tre under control of the longGMR-GAL4 driver caused a mild rough eye phenotype. The eye appeared glassy and smooth. Genotype: UAS-RN-tre/+; longGMR-GAL4/+. (B) Reducing the dosage of Rab5 by 50% enhanced the RN-tre overexpression eye phenotype. The eye became flat and displayed a necrotic phenotype. Genotype: UAS-RN-tre/Rab52; longGMR-GAL4/+. (C) Reducing the dosage of Rab6 did not enhance the RN-tre overexpression eye phenotype. Genotype: UAS-RN-tre/Rab6D23D; longGMR-GAL4/+. (D) Reducing the dosage of Rab11 also significantly enhanced the RN-tre overexpression eye phenotype. Genotype: UAS-RN-tre/+; longGMR-GAL4/Rab11ex2.

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Molecular Brain

ISSN: 1756-6606