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Figure 6 | Molecular Brain

Figure 6

From: A study of long-term potentiation in transgenic mice over-expressing mutant forms of both amyloid precursor protein and presenilin-1

Figure 6

LTP induced by repeated tetani is normal in DbTg mice. (A-C) Pooled data for slices from 2, 6 and 9 month old animals ([black circle] Wt, [white circle] DbTg). (D) Summary of the LTP as a percentage of baseline at 3.5 hours after the last tetanus for the different age groups. (E) Pooled data for slices from 14 month old animals. Traces are taken from the time points immediately prior to induction of LTP and 3.5 h after the last tetanus. Scale bar 0.5 mV, 5 ms. LTP was induced by the delivery of four tetanic stimuli separated by 5 min at the times indicated by the arrowheads.

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Molecular Brain

ISSN: 1756-6606