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Figure 1 | Molecular Brain

Figure 1

From: Sex- and brain region-specific acceleration of β-amyloidogenesis following behavioral stress in a mouse model of Alzheimer's disease

Figure 1

Effects of behavioral stress on Aβ42 levels in the hippocampus and cerebral cortex of 5XFAD mice. Male and female mice were exposed to restraint stress for 6 h per day during 5 consecutive days and were sacrificed for analysis 24 h after the last stress treatment. Levels of total Aβ42 were quantified by sandwich ELISA of guanidine extracts of hippocampal and cortical samples and expressed in nanograms per milligram of total protein (n = 5-8 mice per group). Note that Aβ42 levels are increased specifically in the hippocampus of stressed female 5XFAD mice as compared with non-stressed controls (*p < 0.05). All data are presented as mean ± SEM.

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Molecular Brain

ISSN: 1756-6606