Figure 5
From: Physiological synaptic signals initiate sequential spikes at soma of cortical pyramidal neurons
The prevention of axonal VGSC inactivation by ATX decreases axonal spike thresholds and shortens refractory periods. A) shows the waves of axonal spike thresholds induced by depolarization pulses (50 ms) before and after ATX application (5 μM, green trace). B) shows the averaged values of axonal spike thresholds before and after ATX application. C) shows the waveforms of axonal spike refractory periods induced by depolarization pulses (50 ms) before and after ATX application (5 μM, green trace). D) shows the averaged values of axonal spike refractory periods before and after ATX application.