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Figure 4 | Molecular Brain

Figure 4

From: Copy number loss of (src homology 2 domain containing)-transforming protein 2 (SHC2) gene: discordant loss in monozygotic twins and frequent loss in patients with multiple system atrophy

Figure 4

Structure of copy number loss in the 350-kb subtelomeric region on 19p13.3 resolved by high-density tiling microarray. The moving average log2 ratio (y-axis) is plotted against the genomic position along the chromosome (x-axis). HK06, HK12, HK15, HK19, HK23, and HK28 represent 6 patients with MSA and HK60c and HK78c represent controls. The dark lines indicate the copy number loss. The light lines and dotted lines indicate the normal range and median of the average log2 ratios for probes among normal individuals (n = 25), respectively.

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