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Figure 1 | Molecular Brain

Figure 1

From: Dopamine D1-D2 receptor heteromer signaling pathway in the brain: emerging physiological relevance

Figure 1

Example of Confocal FRET analysis of D1 and D2 receptor interaction in a medium spiney neuron from the core region of rat nucleus accumbens. Anti-D2-Alexa 350 (green) and anti-D1-Alexa 488 (red) were used as donor and acceptor dipoles. The FRET signal was detected and measured in microdomains [regions of interest (ROIs)] within the neuron coexpressing D1 and D2 receptors. Analysis shows the FRET efficiency and the distance separating the dipoles.

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Molecular Brain

ISSN: 1756-6606