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Figure 5 | Molecular Brain

Figure 5

From: ESCRT-III subunits Snf7-1 and Snf7-2 differentially regulate transmembrane cargos in hESC-derived human neurons

Figure 5

Autophagosome formation in hESC-derived human neurons. (A) A CHMP2BWT-transfected human neuron. (B) Autophagosomes accumulate in CHMP2BIntron5-transfected human neurons, as indicated by GFP-LC3. (C) SiRNA knockdown of hSnf7-2 in human neurons leads to autophagosome accumulation, as indicated by GFP-LC3. (D) SiRNA knockdown of hSnf7-1 in human neurons leads to autophagosome accumulation, as indicated by GFP-LC3.

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Molecular Brain

ISSN: 1756-6606