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Figure 1 | Molecular Brain

Figure 1

From: mGluR1,5 activation improves network asynchrony and GABAergic synapse attenuation in the amygdala: implication for anxiety-like behavior in DBA/2 mice

Figure 1

DBA/2 mice show higher anxiety compared to FVB/N mice. An elevated plus-maze was used to evaluate anxiety-like behavior in the strains of DBA/2 and FVB/N mice. A) The diagram shows the experimental methods to examine a mouse staying in the open arms vs. closed ones in an elevated plus-maze. B) shows the mouse position for counting exploration times. C) illustrates the duration for mice staying in the closed arms vs. total duration for each experiment in DBA/2 mice (gray bar) and FVB/N mice (white; p < 0.01, n = 12). D) shows exploration times towards the open arms for DBA/2 mice (gray bar) vs. FVB/N ones (white; p < 0.01, n = 12). The duration for staying in the closed arms is longer and the exploration times are lower significantly in DBA/2 mice than FVB/N mice.

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Molecular Brain

ISSN: 1756-6606