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Figure 3 | Molecular Brain

Figure 3

From: mGluR1,5 activation improves network asynchrony and GABAergic synapse attenuation in the amygdala: implication for anxiety-like behavior in DBA/2 mice

Figure 3

The activities of amygdala neurons are less synchronous in DBA/2 mice than in FVB/N mice. Two-photon cellular imaging was conducted under the frame scanning. A) The picture of chip patterns shows the cross-correlations in the timing phase of activity between two neighboring neurons in DBA/2 mice. Colors from red to blue indicate their cross-correlations from high (synchronous activity) to low. B) shows the cross-correlations between neighboring neurons in FVB/N mice. C) shows a comparison in the cross-correlations averaged from all of the visible amygdala neurons in a FVB/N mouse (red line) and in a DBA/2 mouse (black), in which experiments were done in a single day (p < 0.01). D) illustrates a comparison in the cross-correlations averaged from all of FVB/N mice (red line; n = 11) and DBA/2 ones (black; p < 0.01, n = 12). E) shows a comparison in cross-correlations averaged from all of the astrocytes in FVB/N mice (red line) and DBA/2 ones (black; p = 0.56).

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