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Figure 1 | Molecular Brain

Figure 1

From: Protease activated receptor 1-induced glutamate release in cultured astrocytes is mediated by Bestrophin-1 channel but not by vesicular exocytosis

Figure 1

PAR1 induced glutamate release is blocked by CAAC blockers. A) The experimental scheme of in vitro glutamate release assay using isotope-labeled glutamate (3H-glutamate). 30 μM of TFLLR was treated for 6 min to induce glutamate release from cultured astrocytes.B) Bar graphs represent the averaged relative amount of released glutamate by TFLLR treatment (n=12). 100 μM of Niflumic acid (Nif, n=11) or Flufenamic acid (Flu, n=4) was pretreated to block anion channel activation. **p < 0.05 vs. TFLLR-treated group.

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Molecular Brain

ISSN: 1756-6606