Figure 4
From: Neonatal dexamethasone treatment exacerbates hypoxic-ischemic brain injury
Effect of neonatal DEX treatment on the expression of glutamate uptake transporter proteins in the frontal cortex. (A and B) Representative Western blot and summary bar graph depicting the relative expression levels of GLT-1 (A) and GLAST protein (B) in the frontal cortex from SAL-, DEX-, vehicle (Veh)- and DEX + RU 38486 (RU)-treated groups on P7. (C) A significant inverse correlation was found between the extent of TTC-defined infarct volume 24 hours after HI and the relative levels of GLT-1 protein. (D) The extent of TTC-defined infarct volume 24 hours after HI was not correlated with the relative levels of GLAST protein. The numbers in parentheses indicate the number of animals examined. Data are presented as means ± S.E.M. *P < 0.05 compared with SAL-treated group.