Figure 2
From: Delta-like 1 regulates Bergmann glial monolayer formation during cerebellar development
Abnormal BG in adult Dll1(loxP/loxP)/hGFAP-Cre mice. (A, B) Immunohistochemistry for BLBP (green) in hGFAP-Cre (A) and Dll1(loxP/loxP)/hGFAP-Cre (B) mice. The white arrowheads in (B) show ectopic BG. (C) Quantification of the number of BLBP-positive cell bodies. (D, E) Morphology of BG by Golgi-staining in hGFAP-Cre (D) and Dll1(loxP/loxP)/hGFAP-Cre (E) mice. (F-I) in situ hybridization for GLAST mRNA in hGFAP-Cre (F, G) and Dll1(loxP/loxP)/hGFAP-Cre (H, I) mice. The red arrowheads in (G, I) show ectopic BG. Scale bars: 50 μm (A, B), 10 μm (D,E), 1 μm (F,H), 50 μm (G, I). ML, molecular layer; PCL, Purkinje cell layer.