Figure 4
From: Delta-like 1 regulates Bergmann glial monolayer formation during cerebellar development
The number of BG is reduced in Dll1(loxP/loxP)/hGFAP-Cre mice after P7. (A-D) BrdU incorporation by BG in Dll1(loxP/+)/hGFAP-Cre (A, C) and Dll1(loxP/loxP)/hGFAP-Cre (B, D) mice at P5 (A, B) and P7 (C, D). The cell bodies of BG are labeled with antibodies against BLBP (green) and β-galactosidase (red) antibodies. The red arrowheads in (A-D) show proliferating BG (white). (E, F) Quantification of the number of proliferating BG (white) with incorporated BrdU (sky blue) (E) and BLBP-cell bodies (F) at P5 and P7. Scale bars: 50 μm (A-D). EGL, external granular layer; PCL, Purkinje cell layer.