Microarray analysis of mRNA expression in the LPS-injected SNpc. mRNA expression profiles were compared in intact, and 3 h and 3 d after LPS-injected brain. For each microarray sample, brain tissue blocks (2 × 2 × 2 mm) were obtained from four animals, and total RNA was extracted as described in “Materials and Methods”. Relative mRNA levels of proinflammatory response-related genes (A) and repair/resolution-related genes (B) at 6 h and 3 d after LPS injection are shown as fold-changes normalized to that in the intact SNpc. Data shown are representative of two independent experiments.