Figure 4
From: NMDA receptor subunits have different roles in NMDA-induced neurotoxicity in the retina
TUNEL staining and morphometric analysis following NMDA treatment. (A) Representative photos of TUNEL staining at 1 day after NMDA treatment from WT and GluN2 mutant mice. Scale bar, 20 μm. (B) Quantification of TUNEL-positive cells in the GCL. The data are presented as mean ± S.E.M. of 5 samples for each experiment. **P <0.01 (C) Representative photos of HE staining at 7 days after NMDA and PBS treatment from WT and GluN2 mutant mice. Scale bar, 20 μm. (D-E) Quantification of cell number in the GCL (D) and thickness of IRL (E). The data are presented as mean ± S.E.M. of 5 samples for each experiment. **P <0.01. GCL, ganglion cell layer; INL, inner nuclear layer; ONL, outer nuclear layer; IRL, inner retinal layer.