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Table 2 Plasma levels of β-endorphin

From: Combined analysis of circulating β-endorphin with gene polymorphisms in OPRM1, CACNAD2 and ABCB1 reveals correlation with pain, opioid sensitivity and opioid-related side effects

  N β-endorphin fmol/L p
pain patients 80 26.2(3.59) <0.05
controls 56 28.2(4.63)  
responder 60 26.6(3.57) <0.01
non-responder 20 24.7(3.20)  
Pain patients    
male OPRM1 AA 31 26.8(3.25) <0.05
male OPRM1 AG 8 24.2(2.96)  
female OPRM1 AA 28 26.1(4.02) ns
female OPRM1 AG 11 25.9(3.50)  
Controls    
male OPRM1 AA 19 25.8(2.17) ns
male OPRM1 AG 6 31.5(9.13) ns
female OPRM1 AA 23 29.3(4.60) ns
female OPRM1 AG 8 28.2(1.63) ns
  1. Plasma levels of the opioid peptide β-endorphin in patients with different opioid sensitivity. For further details see Methods and Results.