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Table 2 Plasma levels of β-endorphin

From: Combined analysis of circulating β-endorphin with gene polymorphisms in OPRM1, CACNAD2 and ABCB1 reveals correlation with pain, opioid sensitivity and opioid-related side effects

 

N

β-endorphin fmol/L

p

pain patients

80

26.2(3.59)

<0.05

controls

56

28.2(4.63)

 

responder

60

26.6(3.57)

<0.01

non-responder

20

24.7(3.20)

 

Pain patients

   

male OPRM1 AA

31

26.8(3.25)

<0.05

male OPRM1 AG

8

24.2(2.96)

 

female OPRM1 AA

28

26.1(4.02)

ns

female OPRM1 AG

11

25.9(3.50)

 

Controls

   

male OPRM1 AA

19

25.8(2.17)

ns

male OPRM1 AG

6

31.5(9.13)

ns

female OPRM1 AA

23

29.3(4.60)

ns

female OPRM1 AG

8

28.2(1.63)

ns

  1. Plasma levels of the opioid peptide β-endorphin in patients with different opioid sensitivity. For further details see Methods and Results.