Figure 2

Open field test and Light/dark transition test. (a-d) Open field test: total distance traveled (a), vertical activity (b), time spent in the center of the compartment (c), and stereotypic behavior (d) were recorded. The p-values indicate a genotype effect in the two-way repeated measures ANOVA (a-d, 0–120 minutes; b, 0–30 minutes, 0–60 minutes). Data are given as mean (±SEM). (e-h) Light/dark transition test: distance traveled in the light/dark compartments (e), time spent in the light compartment (f), number of light/dark transitions (g), and latency to enter the light compartment (h) were recorded. The p-values indicate a genotype effect in the two-way repeated measures ANOVA (a-d) or Student’s t-test (e-h). Data are given as mean (±SEM).