Pattern of eIF2α phosphorylation (Ser51) in SK-N-MC neuronal cells infected with HIV alone and together with nicotine. SK-N-MC cells were treated with HIV/nicotine alone and in combination. After 7 days of infection and/or nicotine treatment, eIF2α phosphorylation (at Ser51) was analyzed by western blot assay. We have observed significant eIF2α phosphorylation in HIV and HIV + nicotine treated groups when compared with the control cells. (*, p ≤ 0.05; NS-Not Significant).