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Figure 2 | Molecular Brain

Figure 2

From: Effects of NB001 and gabapentin on irritable bowel syndrome-induced behavioral anxiety and spontaneous pain

Figure 2

Behavioral tests of zymosan-treated mice. (A) A volume of 0.1 ml zymosan (30 mg/ml) or saline was injected transanally into the colons of mice via a needle connected to a PE tube. (B) After injections on three consecutive days, behavioral tests were administered to zymosan- and saline-treated mice on days 1, 7, 14 and 28 (n = 6 mice per group). (C) The number of pain behaviors observed in zymosan-treated mice on days 1, 7, 14 and 28 increased significantly compared to saline-treated mice (n = 6 mice per group). * denotes a significant difference between zymosan- and saline-treated mice. “Before” designated the mice before saline or zymosan intracolonic treatment.

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Molecular Brain

ISSN: 1756-6606