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Figure 2 | Molecular Brain

Figure 2

From: Cdk5/p35 functions as a crucial regulator of spatial learning and memory

Figure 2

Normal locomotor activity and reduced anxiety-like behavior in CreER-p35 cKO mice (A) Total distance (cm) and percentage time spent in the center region of the open field in p35-flox (white bars, control, n =6) and CreER-p35 cKO mice (black bars, p35 cKO, n =8). No difference was observed between these. (B) Total distance (cm) and percentage time spent in closed and open arms in the elevated plus maze in p35-flox (white bars, control, n =6) and CreER-p35 cKO mice (black bars, p35 cKO, n =8). CreER-p35 cKO mice traveled a similar distance when compared with control and displayed less anxiety-like behavior. Error bars represent standard error of the mean (S.E.M.). Unpaired t-test, *p<0.05.

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