Figure 6
From: Genome-wide screen for modifiers of Na+/K+ATPase alleles identifies critical genetic loci
Genetic interactions between FKBP59 and ATPalpha . FKBP59; ATPalpha double mutants and ATPalpha*, FKBP59 RNAi flies were assayed and compared to ATPalpha* heterozygous controls. The RNAi knockdown was driven with da-Gal4. The genotypes in each graph are: ATPalpha*/+ (green), FKBP59E03444/+; ATPalpha*/+ (red), daGal4,ATPalpha*/+ (blue), and FKBP59-RNAi/+;daGal4,ATPalpha*/+ (orange). FKBP59 mutants significantly enhanced the ATPalphaDTS1 phenotype. The ATPalphaCJ5 phenotype is suppressed by both the FKBP59 mutant and RNAi. *p < 0.05, **p < 0.01, ***p < 0.001.