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Figure 8 | Molecular Brain

Figure 8

From: Evidence that the presynaptic vesicle protein CSPalpha is a key player in synaptic degeneration and protection in Alzheimer’s disease

Figure 8

Mice expressing human tau have an age-dependent CSPalpha upregulation that correlates with neuroprotection. (A) CSPalpha expression in hippocampus of young (3–4 months) wild type (n = 6) and htau mice (n = 6). (B) CSPalpha expression in cortex of young (3–4 months) wild type (n = 6) and htau mice (n = 6). (C) CSPalpha expression in cerebellum of the same mouse sample as in panel (A) and (B). (D) CSP alpha expression in old (24 months) wild type (n = 4) and htau mice (n = 7). CSPalpha expression was normalized against NSE in all panels. Panel (E) shows the representative western blots. Means ± s.e.m are shown. ***, p < 0.001.

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Molecular Brain

ISSN: 1756-6606