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Figure 5 | Molecular Brain

Figure 5

From: The novel protein kinase C epsilon isoform at the adult neuromuscular synapse: location, regulation by synaptic activity-dependent muscle contraction through TrkB signaling and coupling to ACh release

Figure 5

nPKCε regulates phosphorylation of MARCKS in skeletal muscle. (A) shows the Western blotting analysis of nPKCε, pnPKCε, pMARCKS and Hsp70 in control adult muscles (Ctr) and after incubation with peptide εV1-2 (10 min). (B) shows the time course of the level of pMARCKS in adult diaphragm muscle in resting conditions after muscle dissection. (C) shows the Western blotting analysis of pMARCKS and syntaxin in denervated EDL muscle. The quantitative histograms in A and C show the percentage of changes respect to the control and normalized with actin. The data are mean ± SD values from at least 5 independent experiments. *p < 0.05. Experiments were performed using diaphragm muscle.

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Molecular Brain

ISSN: 1756-6606