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Figure 4 | Molecular Brain

Figure 4

From: Differential expression of hyperpolarization-activated cyclic nucleotide-gated channel subunits during hippocampal development in the mouse

Figure 4

Expression of HCN2 in PV-positive cells of the hippocampus at P21. (A-B, D-F, H-J, L-N, P): The images show HCN2 labeling in different fields of the hippocampus and the DG. (A, E, I): Note that HCN2 expression was more prominent in the sl-m and sp of the CA, particularly in CA3. Interestingly, the alveus did not show HCN2 expression at this developmental stage. In addition, the sl-m and sp of the CA3 (I) presented stronger labeling than in the CA1 (A) and the CA2 (E). Most PV-immunopositive cells located in the sp of the CA1 (A, B, D), CA2 (E, F, H), CA3 (I, J, L), and hilus of the DG (M, N, P) co-expressed HCN2. A-B, D-F, H-J, L-N, P: white arrows indicate PV-positive/HCN2-positive cells. C, G, K, O: DAPI staining. Scale bars = 20 μm.

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Molecular Brain

ISSN: 1756-6606