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Table 1 Density of HCN isoform expression in the hippocampus at P21 and P56

From: Differential expression of hyperpolarization-activated cyclic nucleotide-gated channel subunits during hippocampal development in the mouse

 

HCN1

HCN2

HCN4

 

3 weeks

8 weeks

3 weeks

8 weeks

3 weeks

8 weeks

CA1

      

SL-M

++

++++

++++

++++

++++

++

SR

+

-

-

+

-

+

SP

+

+

++

+

++

+

SO

-

-

-

+

-

+

Alveus

++++

++++

-

++

-

++

CA2

      

SL-M

++

+++

++++

++++

++++

++

SR

+

-

-

+

-

+

SP

++

+

++

+

++

+

SO

+

-

+

+

+

+

Alveus

++++

++++

-

++

-

++

CA3

      

SL-M

++

+++

++++

++

++++

++

SR

++

++

-

+

+

+

SL

-

-

-

-

++

-

SP

+++

+++

++++

+++

++++

++

SO

+

+

-

+

+

+

Alveus

++++

++++

-

+

+

+

Dentate gyrus

      

ML

-

-

++

+

+

+

GCL

+

+

++

+

+

+

hilus

++

+

++

++

+

++

  1. ++++, very high expression; +++, high expression; ++, moderate expression; +, low expression; −, no detection.