Figure 6
Summary data of immunoblot and dot-blot (HNE) analysis of age-related changes in various AD- and synapse-related markers (panels A-I, as indicated) in hippocampal homogenates (30 μg protein) from wildtype or Aldh2 -/- mice. Immunoreactive bands or spots were quantitated by densitometry. Data are presented as the mean ± SD (n = 4 mice) and were analyzed by a two-way ANOVA with a Bonferroni post-hoc test. *, significant differences from wildtype (*p < 0.05, ***p < 0.001); ψ, significant age-related differences as indicated (ψ p < 0.05, ψψ p < 0.001, ψψψ p < 0.001).