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Fig. 3 | Molecular Brain

Fig. 3

From: Differentiation of multipotent neural stem cells derived from Rett syndrome patients is biased toward the astrocytic lineage

Fig. 3

Immunostaining of neural cells derived from RTT-hiPSCs and gene expression analysis of hiPSC-derived neural cells. (A) Immunostaining was performed to evaluate expression levels of MeCP2 (red), the neuronal marker, MAP2 (green), and the astrocytic marker, GFAP (magenta) in RTT-hiPSC-derived neural cells. Ho, Hoechst (blue). Arrowhead indicated MAP2, MeCP2 and Hoechst positive cells. Scale bar, 50 μm. (B) Results of PCA (performed by using MeV software (TIGR) Software) of microarray gene expression in RTT-hiPSC lines and neural cells differentiated from RTT-hiPSC lines. N, neural cells differentiated from hiPSC lines. (C) Scatter plots of microarray gene expression in hiPSC-RTT lines and neural cells differentiated from hiPSC-RTT lines. Neural cells were co-cultured for ~30 days with mouse astrocytes

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Molecular Brain

ISSN: 1756-6606