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Fig. 5 | Molecular Brain

Fig. 5

From: Nicotine attenuates the effect of HIV-1 proteins on the neural circuits of working and contextual memories

Fig. 5

Regulation of synaptic plasticity gene expression by nicotine in the hippocampus (a) and amygdala (b) of F344 rats. Moderate chronic dose of nicotine increased expression of genes in the Ca+2/calmodulin-dependent kinase-IV signaling and Raf/Mek/Erk signaling pathways in the hippocampus. However, the same dose of nicotine downregulated the majority of synaptic plasticity genes in the amygdala compared with the F344 saline-treated group. Signaling cascades were drawn by IPA

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Molecular Brain

ISSN: 1756-6606