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Fig. 7 | Molecular Brain

Fig. 7

From: Palmitoylethanolamide reduces pain-related behaviors and restores glutamatergic synapses homeostasis in the medial prefrontal cortex of neuropathic mice

Fig. 7

Release of D-Aspartate (a) or glutamate (b) in sham or SNI mice 30 days after injury. The values of extracellular amino acids in the mPFC were expressed as pmol in 10 μl of perfusate. Each point represents the mean ± S.E.M of 7–8 animals per group. P < 0.05 was considered statistically significant. ANOVA, post hoc Tukey. “c” shows a typical HPLC determination of D-Asp, L-Asp and Glutamate in neuropathic mice. “d” shows the same sample as in A after treatment with DDO. The peak corresponding to D-Asp disappears because of oxidation by DDO. The arrow shows the elution of D-Asp

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Molecular Brain

ISSN: 1756-6606