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Fig. 3 | Molecular Brain

Fig. 3

From: A septo-temporal molecular gradient of sfrp3 in the dentate gyrus differentially regulates quiescent adult hippocampal neural stem cell activation

Fig. 3

A gradient of sfrp3 expression in dentate gyrus from early postnatal to aged animals. a Representative images of sfrp3 mRNA in situ in the dentate gyrus of wildtype mice at different ages (P7, P10, P56 and P360). Scale bar, 250 μm. b Quantification of signal intensity for sfrp3 in situ, which was performed on the images shown in Fig. 3a. Reconstructed dentate gyri from sagittal sections were divided into 100 bins (represented on the X axis) for quantification of signal intensity along the septo-temporal axis. Values represent mean ± S.E.M. (n = 3). The sfrp3 mRNA expression increases from septal to temporal dentate gyrus at each age from P7 to P56 in WT mice with an increase in slope during the interval of P7-P56

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Molecular Brain

ISSN: 1756-6606