Fig. 7
From: PARP-1 activity is required for the reconsolidation and extinction of contextual fear memory
Inhibition of PARP-1 activity does not affect locomotor activity or anxiety-related behavior. a, b Effects of a micro-infusion of 3AB into the dorsal hippocampus (a) or mPFC (b) at 5 min before the open field test (dorsal hippocampus: VEH, n = 7; 3AB, n = 8; mPFC: VEH, n = 9; 3AB, n = 9). c Effects of a systemic injection of Tiq-A at 30 min before the open field test (VEH, n = 20; Tiq-A, n = 20). Total path length for 5 min (left panel). Percentage of time spent in the center for 5 min (right panel). Error bars indicate SEM