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Fig. 5 | Molecular Brain

Fig. 5

From: Mesenchymal stem cells suppress neuronal apoptosis and decrease IL-10 release via the TLR2/NFκB pathway in rats with hypoxic-ischemic brain damage

Fig. 5

MSC co-culture suppressed apoptosis in OGD-injured PC12 cells. a Annexin V-FITC/PI double staining of PC12 cells in the control, OGD and OGD + MSCs groups. a, d and g. Annexin-V-positive PC12 cells in the control, OGD and OGD + MSCs groups. b, e and h. PI-positive PC12 cells in the control, OGD and OGD + MSCs groups. c, f and i. Annexin-V-positive cells and PI-positive cells merged with bright-field images of PC12 cells in the control, OGD and OGD + MSCs groups. Scale bar = 100 μm. b-c Annexin-V and PI sum intensity of PC12 cells in the control, OGD and OGD + MSCs groups. n = 5 in each group. The results are presented as the mean ± SEM. # P < 0.05 vs. control PC12 cells; &P < 0.05 vs. OGD-injured PC12 cells

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