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Table 1 Effects of ADX92639 or its vehicle on body temperature at different times (1-58 h) after first administration

From: Targeting type-2 metabotropic glutamate receptors to protect vulnerable hippocampal neurons against ischemic damage

Hours

Vehicle

ADX92639

0

36.9 ± 0.3

37.0 ± 0.1

1

36.4 ± 0.3

36.5 ± 0.3

3

35.9 ± 0.1

36.1 ± 0.1

6

35.8 ± 0.1

35.8 ± 0.1

9

37.0 ± 0.1

36.9 ± 0.2

24

36.2 ± 0.1

36.2 ± 0.4

25

35.9 ± 0.0

35.8 ± 0.1

27

35.9 ± 0.0

35.9 ± 0.1

30

36.2 ± 0.2

36.3 ± 0.2

33

36.8 ± 0.3

36.1 ± 0.2

48

36.0 ± 0.1

35.9 ± 0.0

49

36.1 ± 0.0

36.1 ± 0.0

52

36.1 ± 0.1

36.1 ± 0.1

55

36.2 ± 0.0

36.2 ± 0.1

58

36.7 ± .03

36.5 ± 0.3

  1. Effect of oral treatment with ADX92639 (30 mg/kg) or vehicle on body temperature in normal rats. ADX92639 or vehicle were administered three times with 24 h of interval. Rectal temperature was measured at different times (1-58 h) after the first administration of ADX92639 or vehicle. Value are means ± S.E.M. (n = 3)