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Fig. 2 | Molecular Brain

Fig. 2

From: Human induced pluripotent stem cell derived neurons as a model for Williams-Beuren syndrome

Fig. 2

WBS-neurons display prolonged decay of evoked action potentials and decreased voltage-gated K+ currents. a Spontaneous action potentials were identified in WT- (Left) and WBS- (Right) neurons. b Representative traces show membrane potentials responding to injection of current step in WT- (Left) and WBS- (Right) neurons. c-d Histograms represent average decay time and amplitude of evoked action potentials for all cell lines of WT- and WBS-neurons. “n” represents number of neurons recorded. *P < 0.05, **P < 0.01. e A plot showing average current–voltage relationships of voltage-gated Na+ and K+ currents between WT- and WBS-neurons. ***P < 0.001

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