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Fig. 4 | Molecular Brain

Fig. 4

From: Opposing presynaptic roles of BDNF and ProBDNF in the regulation of persistent activity in the entorhinal cortex

Fig. 4

BDNF-induced facilitation of persistent firing is independent of p75NTR. a Pre-incubation with p75NTR function-blocking antibodies does not occlude BDNF potentiating effects on persistent firing elicited at 2.5 μM CCh. Quantification of plateau potential amplitudes (b) and firing frequencies (c). * p < 0.05, *** p < 0.001 ANOVA followed by Tukey multiple comparison. Statistics are shown for vehicle (n = 4) vs. BDNF (n = 4) and p75NTR Ab (n = 3) vs. p75NTR Ab + BDNF (n = 3)

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