Fig. 5
From: Altered DNA base excision repair profile in brain tissue and blood in Alzheimer’s disease
PARP1, APE1 and Polβ protein levels are modified in AD. Quantitative protein detection was performed by mass spectrometry (nLC and Thermo Q Exactive). Levels of base excision repair proteins PARP1, APE1 and Polβ were compared in Alzheimer’s patients (AD) and healthy controls (HC). Reference to house-keeping proteins is shown in Additional file 1: Figure S1. Black bars: PARP1, grey bars: APE1, light grey bars: Polβ. DNA glycosylase OGG1 was below the detection limit. Abbreviations: FC = Frontal cortex, CB = Cerebellum