Fig. 7
From: Zbtb20 modulates the sequential generation of neuronal layers in developing cortex
Schematic summary of the observed effects of Zbtb20 on the temporal acquisition of identity by the cortical glutamatergic projection neurons. a Arrangement of cortical pyramidal neurons in WT mice and their normal time windows of generation. b Layer defects in Zbtb20 lacZ/lacZ mice and the respective changes in the time windows for neuronal generation. Note the increase of L6, L5 and L4 neurons and the diminishing of L3 and L2 neurons. A few ROR+ (L4) cells can even be seen intermingled with L3/L2 cells. Some L3/L2 cells are retained in the subcortical white matter and LLs