Fig. 5
![Fig. 5](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs13041-016-0243-1/MediaObjects/13041_2016_243_Fig5_HTML.gif)
Treatment with n-EMVs and OGD-EMVs reversely influenced the permeability of BBB and ZO-1/Claudin-5 expression. a n-EMVs reduced while OGD-EMVs increased the permeability of BBB. b, c Representative images of ZO-1 (b) and Claudin-5 (c) staining on HBMECs. Scale bar, 50 μm. d Western blot analyses of ZO-1 and Claudin-5. (* p <0.05, ** p <0.01, vs. vehicle, n = 5)